Research Interests
Lipids in Virology
I use computer simulations to explore the mechanics of virus entry, self-assembly, and cellular manipulation. Understanding viral transitions to new hosts is a fascinating challenge. I am mainly working on Influenza A, SARS-CoV-2, and Ebola viruses.
Lipid Binding Proteins
I'm intrigued by how certain proteins exhibit selectivity in binding to specific lipids within the cell membrane and how the composition of membrane lipids profoundly influences these interactions, shaping protein conformation and orientation within the cellular environment.
Lipid Transfer Proteins
I'm fascinated by how proteins take and release lipids from the cell membranes and how the membrane lipid composition affects these interactions and the directionality of lipid transport.
Self-assembly and Pore Forming Proteins
My current focus revolves around unraveling the physical-chemical properties of pore-forming proteins via computer simulations. My primary research centers on the intricate characteristics of BAX/BOK, GSDM, and FGF2 proteins.
Computational Structure Biology
By employing advanced techniques such as docking, modeling, and molecular dynamics simulations, I refine Cryo-EM/ET, NMR, crystallography with AI-powered structural predictions to understand intricate 3D biomolecular architectures and their interaction with membranes.